Auto immune diseases

Subject : Science and technology

Concept :

Evidence suggests that obese individuals have a higher risk of developing autoimmune diseases such as type 1 diabetes.
A possible mechanism that could explain this connection — metabolic overload that suppresses immunoregulation and induces inflammatory responses, thereby increasing the risk of autoimmunity.

Auto Immune Diseases

Autoimmune diseases arise from an abnormal immune response of the body against substances and tissues normally present in the body (autoimmunity). This may be restricted to certain organs or involve a particular tissue in different places.
A large number of autoimmune diseases are recognized.
It has been estimated that autoimmune diseases are among the top ten leading causes of death among women in all age groups up to 65 years. A substantial minority of the population suffers from these diseases, which are often chronic, debilitating, and life-threatening. There are more than 80 illnesses caused by autoimmunity.
Normally our immune system produces proteins called antibodies that protect the body from these invaders.
Autoimmune means our immune system cannot tell the difference between these foreign invaders and our body’s healthy tissues (“auto” means “self”) and creates auto-antibodies that attack and destroy healthy tissue. These auto-antibodies cause inflammation, pain, and damage in various parts of the body.
The treatment of autoimmune diseases is typically with immunosuppression—medication that decreases the immune response.