Whole Genome Sequencing (WGS)

Whole Genome Sequencing (WGS)

Subject – Science and Tech

Context – More Omicron cases detected in TN; fresh curbs imposed

Concept –

• Whole genome sequencing is the process of determining the complete DNA sequence of an organism’s genome at a single time.
• This entails sequencing all of an organism’s chromosomal DNA as well as DNA contained in the mitochondria and, for plants, in the chloroplast.
• In practice, genome sequences that are nearly complete are also called whole genome sequences.
• The whole genome sequencing relies on new technologies that allow rapid sequencing of the entire genome in a matter of a few days.

Genome Sequencing:

• Genome Sequencing means deciphering the exact order of base pairs in an individual.

• In this particular piece of DNA, an adenine (A) is followed by a guanine (G), which is followed by a thymine (T), which in turn is followed by a cytosine (C), another cytosine (C), and so on.