‘10000 genome’ project completed, says govt.

Subject: Science and tech

Section: Biotech

Context:

The Department of Biotechnology (DBT) in India has completed the ‘10000 genome’ project, aiming to create a comprehensive reference database of whole-genome sequences specific to India’s diverse population.

10,000 Genome Project:

This project, which marks a significant step since India sequenced its first complete human genome in 2006, involves about 20 institutions, with the Indian Institute of Science (IISc), Bengaluru, and the Centre for Cellular and Molecular Biology, Hyderabad leading the coordination.
The initiative addresses the genetic diversity within India’s 1.3 billion population, which includes over 4,600 population groups, many of which are endogamous, leading to distinct genetic variations and a higher frequency of certain disease-causing mutations within these groups.
The project’s goals include enhancing an understanding of India’s population diversity, improving diagnostics and medical counselling, developing personalized drugs, advancing gene therapy, and investigating individual susceptibility to infectious diseases.
A biobank housing 20,000 blood samples has been established at the IISc for future research, highlighting the project’s dedication to transparency and collaboration.

Source: TH