AI tool developed to study cancer-causing mutations

AI tool developed to study cancer-causing mutations

Subject: Science & tech

Context: Researchers at IIT Madras have developed an AI tool called NBDriver (neighborhood driver) for use in analyzing cancer-causing mutations in cells.

Concept:

• The Indian Institute of Technology (IIT) Madras researchers have formulated an artificial intelligence-based mathematical model.
• The AI algorithm will spot cancer-causing changes in cells.
• This algorithm studies DNA structures to characterize the genetic changes responsible for cancer progression, which are responsible for causing cancer.
• Using simple AI techniques, the researchers developed a new prediction algorithm, NBDriver, and tested its performance on several open-source cancer mutation datasets.
• NBDriver (NEIGHBORHOOD Driver) is a tool used to differentiate between driver and passenger mutations using features derived from the neighborhood sequences of somatic mutations.