Drugs in India to fight Covid
- June 9, 2020
- Posted by: OptimizeIAS Team
- Category: DPN Topics
Subject: Science and tech
- Remdesivir, an antiviral drug first developed for treating Ebola in 2014, is one of the possible Covid-19 treatments being investigated in the WHO’s Solidarity Trial.
- It inhibits viral replication in the body.
- Favipiravir is an antiviral given to inhibit viral replication.
- It is used as an anti-influenza drug.
- This is an immunosuppressant commonly used to treat for rheumatoid arthritis.
- In Mumbai, more than 100 severely ill Covid patients have been treated with this expensive drug (Rs 40,000-60,000 per dose) as a preventive against ventilator requirement
- This antimalarial drug is a subject of debate over its efficacy against Covid.
- The WHO halted its HCQ arm in the Solidarity Trial following a study in The Lancet, then reinstated it after a retraction by the authors.
- India is the largest producer of this drug. Doctors use HCQ use in Covid patients with symptoms as mild as headache, fever, body pain, and even in critically ill patients. ICMR guidelines recommend low doses for nine days.
Doxycycline + ivermectin
- Doxycycline is an antibiotic used to fight infection in the urinary tract, eye, or respiratory tract.
- Ivermectin is an anti-parasite drug for treatment of scabies, head lice, and filariasis.
- The combination is used to treat Covid patients with acute symptoms.
Ritonavir + lopinavir
- These antivirals are commonly used to treat HIV patients.
- They are being investigated in the Solidarity Trial.
- This is meant for critical patients with low oxygen saturation levels, or those suffering a cytokine storm.
- Patients who have recovered from severe Covid-19 donate their plasma, which is then injected into other critical patients to boost their immunity.
- A protocol approved by ICMR is used to select which patient is best suited for plasma therapy. Preference is given to those at risk of cytokine storm, extreme breathlessness with severe pneumonia.