FASTING & CALORIE RESTRICTION FOR HEALTHY LIFESPAN
No Comments
FASTING & CALORIE RESTRICTION FOR HEALTHY LIFESPAN
TOPIC: Science & Tech
Context- A study of data from 186 countries in the journal The Lancet revealed that obese people now out number underweight individuals.
Concept-
Fasting versus CR:
| Fasting | Calorie Restriction |
| Fasting is the willful refrainment from eating and sometimes drinking. There are several strategies for fasting. ● In intermittent fasting (IF) is an alternate 24 hour period without any food with 24 hours of normal eating. ● In periodic fasting fast for one or two days followed by five days of normal diet. ● In time restricted feeding (TRF), all daily intake is done within a 4–12 hour window. | CR results from reducing caloric intake by 15% to 40%, without leading to malnutrition. |
- We store glucose in the form of glycogen in the liver, and the energy demands of the body are met from this reservoir.
- One day of fasting leads to a 20% decrease in blood sugar levels and depleted glycogen reserves.
- The body switches to a metabolic mode where energy is obtained from fat derived ke tone bodies and from glucose outside the liver.
- In the fruit fly, prolonged overnight fasting promotes a recycling process inside cells called autophagy.
- Autophagy mostly occurs at night and is modulated by the body’s circadian clock.
- Autophagy is essential for the fitness and survival of neuron.
- It has also been shown to cause a remodelling of the gut microbiome increasing Bacteria diversity.