- October 30, 2022
- Posted by: OptimizeIAS Team
- Category: DPN Topics
Subject: Science and Technology
- In a major breakthrough in creating immunity in cattle against infectious diseases, including mastitis, researchers of the Transdisciplinary University of Health Sciences & Technology (TDU), Bengaluru, have successfully validated the immunomodulation ability of a natural phytochemical compound with curcumin as the active ingredient.
The severity of mastitis in India-
- At a time when economic loss due to mastitis in India exceeds ₹13,000 crore annually, there is great relevance for the findings as no vaccination is available against mastitis yet.
- Antibiotics have been used to manage various infections in cattle.
- However, it has been noticed that the uncontrolled use of antibiotics results in increased antibiotic resistance.
What the research found-
- The study was carried out in the Thrissur district in Kerala as part of the academia-industry interface.
- Research findings revealed that the natural product offers immunity in dairy cattle against infectious diseases, including mastitis, by increasing complementary protein, interferon, immunoglobulin (IgM), lymphocytes and monocytes.
- An increase in calcium-phosphorus and albumin-globulin ratio and digestibility index substantiates a 10% increase in milk production.
Significance of the research-
- For States like Kerala where more than 96% cattle are crossbreeds, control of mastitis assumes more significance.
- The use of antibiotics for treating mastitis results in interspecies and intergenus transfer of antibiotic resistance and the creation of various multidrug-resistant microorganisms in the environment, which affects the immunity of livestock and human health.
- The compound with curcumin can be used to control mastitis as a prophylactic measure during the prepartum and postpartum stages along with cattle feed under scientific management practices.
About the Mastitis-
- Mastitis, or inflammation of the mammary gland, is the most common and the most expensive disease of dairy cattle throughout most of the world.
- Several types of bacteria cause distinctly different mastitis infections.
- Antibiotic infusions into the udder nearly always cure the clinical disease but may not eliminate the bacterial infection.
- Although stress and physical injuries may cause inflammation of the gland, infection by invading bacteria or other microorganisms (fungi, yeasts and possibly viruses) is the primary cause of mastitis.
- Infections begin when microorganisms penetrate the teat canal and multiply in the mammary gland.