Significance of an influenza A (H1N2)v case in the U.K.
- December 17, 2023
- Posted by: OptimizeIAS Team
- Category: DPN Topics
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Significance of an influenza A (H1N2)v case in the U.K.
Subject : Science and Tech
Section: Health
Context:
- The United Kingdom Health Security Agency (UKHSA) reported the first known human case of influenza A (H1N2)v in the UK, a variant of the influenza virus previously not known to cause infections in humans.
More about the news:
- Health officials in the UK are investigating the first confirmed case of a new strain of swine flu, identified as A(H1N2)v.Â
- The virus is similar to those circulating in pigs in the UK.
- The infected person, detected during routine flu screening in North Yorkshire, is being closely monitored, and contacts are being traced.
- This is the first time A(H1N2)v has been found in humans in the UK, though it resembles viruses previously detected in pigs.
- Influenza A(H1) viruses are common in swine globally.
- Investigations are ongoing to determine how the individual contracted the virus.
- A total of 50 human cases of A(H1N2)v have been reported globally since 2005, and this strain has not been previously detected in humans in the UK.
- The UK case represents a distinct clade (1b.1.1), different from recent global cases but similar to viruses in UK pigs.
About Swine flu:
- Swine influenza, also called pig influenza, is an infection caused by any one of several types of swine influenza viruses. Swine influenza virus or swine-origin influenza virus is any strain of the influenza family of viruses that is endemic in pigs.
- Influenza A (H1N1) virus is the subtype of influenza A virus that is the most common cause of human influenza.
- It is an orthomyxovirus that contains the glycoproteins haemagglutinin and neuraminidase.
- For this reason, they are described as H1N1, H1N2 etc. depending on the type of H or N antigens they express with metabolic synergy.
- Haemagglutinin causes red blood cells to clump together and binds the virus to the infected cell.
- Neuraminidase is a type of glycoside hydrolase enzyme which helps to move the virus particles through the infected cell and assist in budding from the host cells.
- Some strains of H1N1 are endemic in humans and cause a small fraction of all influenza-like illness and a small fraction of all seasonal influenza. Other strains of H1N1 are endemic in pigs (swine influenza) and in birds (avian influenza).