- May 15, 2021
- Posted by: admin1
- Category: DPN Topics
Subject: Science & tech
Context: Recently, Dr Reddy’s Laboratories (DRL) has said that it had launched Sputnik V in India. The vaccine is currently the second most expensive Covid-19 jab in the country.
About Sputnik V
- It is made by the Gamaleya Research Institute of Epidemiology and Microbiology in Moscow.
- It is a two-dose Covid-19 vaccine using a similar platform to Covishield.
- Unlike Covishield, which uses a weakened common cold “adenovirus” that affects chimpanzees, Sputnik V makes use of two different human adenoviruses.
- The vaccine has an efficacy of over 91 per cent.
- It implies that Sputnik V has the ability to bring down symptomatic Covid-19 cases by over 91 per cent in those vaccinated compared with those who have not received a Covid vaccine.
- In India, Dr Reddy’s Laboratories is the local distribution partner for Sputnik V.
- It works on a complex biotechnology in which another virus is employed to carry the DNA code required for triggering immune response in human cells.
Working of Sputnik V Vaccine
- It uses two different viruses that cause the common cold (adenovirus) in humans.
- The adenoviruses are weakened so they cannot replicate in humans and cannot cause disease.
- They are also modified so that the vaccine delivers a code for making the coronavirus spike protein.
- It aims to ensure that when the real virus tries to infect the body, it can mount an immune response in the form of antibodies.
- Sputnik uses a different vector for each of the two shots in a course of vaccination.
- It provides immunity with a longer duration than vaccines using the same delivery mechanism for both shots.